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The N-end rule pathway and regulation by proteolysis

The N-end rule relates the regulation of the in vivo half-life of a protein to the identity of its N-terminal residue. Degradation signals (degrons) that are targeted by the N-end rule pathway include a set called N-degrons. The main determinant of an N-degron is a destabilizing N-terminal residue o...

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Detalhes bibliográficos
Autor principal: Varshavsky, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189519/
https://ncbi.nlm.nih.gov/pubmed/21633985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.666
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