Role of 20-Hydroxyeicosatetraenoic Acid in Mediating Hypertension in Response to Chronic Renal Medullary Endothelin Type B Receptor Blockade

BACKGROUND: The renal medullary endothelin (ET-1) system plays an important role in the control of sodium excretion and arterial pressure (AP) through the activation of renal medullary ET-B receptors. We have previously shown that blockade of endothelin type B receptors (ET-B) leads to salt-sensitiv...

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Bibliographic Details
Main Authors: Speed, Joshua S., George, Eric M., Arany, Marietta, Cockrell, Kathy, Granger, Joey P.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189228/
https://ncbi.nlm.nih.gov/pubmed/22016812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026063
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