Iron Insufficiency Compromises Motor Neurons and Their Mitochondrial Function in Irp2-Null Mice

Genetic ablation of Iron Regulatory Protein 2 (Irp2, Ireb2), which post-transcriptionally regulates iron metabolism genes, causes a gait disorder in mice that progresses to hind-limb paralysis. Here we have demonstrated that misregulation of iron metabolism from loss of Irp2 causes lower motor neuro...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Jeong, Suh Young, Crooks, Daniel R., Wilson-Ollivierre, Hayden, Ghosh, Manik C., Sougrat, Rachid, Lee, Jaekwon, Cooperman, Sharon, Mitchell, James B., Beaumont, Carole, Rouault, Tracey A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189198/
https://ncbi.nlm.nih.gov/pubmed/22003390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025404
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados