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Speed limit of protein folding evidenced in secondary structure dynamics

As the simplest and most prevalent motif of protein folding, α-helix initiation is the starting point of macromolecular complexity. In this work, helix initiation was directly measured via ultrafast temperature-jump spectroscopy on the smallest possible helix nucleus for which only the first turn is...

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Detalhes bibliográficos
Main Authors: Lin, Milo M., Mohammed, Omar F., Jas, Gouri S., Zewail, Ahmed H.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3189027/
https://ncbi.nlm.nih.gov/pubmed/21949361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1113649108
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