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Hydrophobic forces and the length limit of foldable protein domains
To find the native conformation (fold), proteins sample a subspace that is typically hundreds of orders of magnitude smaller than their full conformational space. Whether such fast folding is intrinsic or the result of natural selection, and what is the longest foldable protein, are open questions....
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3382496/ https://ncbi.nlm.nih.gov/pubmed/22665780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207382109 |
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