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Increased hedgehog signaling in postnatal kidney results in aberrant activation of nephron developmental programs
Hedgehog (Hh) is a core signaling pathway implicated in fundamental processes during embryonic kidney development. We previously found that loss-of-function mutations in the transcription factor GLIS2, a putative vertebrate ortholog of Drosophila Ci, cause nephronophthisis type 7 in humans and mice....
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3188992/ https://ncbi.nlm.nih.gov/pubmed/21816948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr339 |
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