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Dual inhibition of epidermal growth factor and insulin-like 1 growth factor receptors reduce intestinal adenoma burden in the Apc(min/+) mouse
BACKGROUND: Identification of early molecular pathway changes may be useful as biomarkers for tumour response/resistance prediction, and here we provide direct in vivo proof of this concept. The type 1 insulin-like growth factor receptor (IGF1R) has been implicated in various aspects of adenoma deve...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
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Nature Publishing Group
2011
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3188935/ https://ncbi.nlm.nih.gov/pubmed/21811251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2011.291 |
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