Ciliary neurotrophic factor activates leptin-like pathways and reduces body fat, without cachexia or rebound weight gain, even in leptin-resistant obesity

Ciliary Neurotrophic Factor (CNTF) was first characterized as a trophic factor for motor neurons in the ciliary ganglion and spinal cord, leading to its evaluation in humans suffering from motor neuron disease. In these trials, CNTF caused unexpected and substantial weight loss, raising concerns tha...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Lambert, P. D., Anderson, K. D., Sleeman, M. W., Wong, V., Tan, J., Hijarunguru, A., Corcoran, T. L., Murray, J. D., Thabet, K. E., Yancopoulos, G. D., Wiegand, S. J.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC31889/
https://ncbi.nlm.nih.gov/pubmed/11259650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.061034298
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker