Precise Scheduling of Chemotherapy Primes VEGF-producing Tumors for Successful Systemic Oncolytic Virotherapy

We have previously reported that a burst of vascular endothelial growth factor (VEGF) signaling to tumor-associated endothelium induces a proviral state, during which systemically delivered oncolytic reovirus can replicate in endothelium, thereby inducing immune-mediated vascular collapse and signif...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kottke, Timothy, Chester, John, Ilett, Elizabeth, Thompson, Jill, Diaz, Rosa, Coffey, Matt, Selby, Peter, Nuovo, Gerard, Pulido, Jose, Mukhopadhyay, Debabrata, Pandha, Hardev, Harrington, Kevin, Melcher, Alan, Vile, Richard
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2011
Schlagworte:
Original Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188745/
https://ncbi.nlm.nih.gov/pubmed/21792179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2011.147
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