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Structural Determinants of Opioid and NOP Receptor Activity in Derivatives of Buprenorphine

The unique pharmacological profile of buprenorphine has led to its considerable success as an analgesic and as a treatment agent for drug abuse. Activation of nociceptin/orphanin FQ peptide (NOP) receptors has been postulated to account for certain aspects of buprenorphine’s behavioural profile. In...

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Detalhes bibliográficos
Main Authors: Cami-Kobeci, Gerta, Polgar, Willma E., Khroyan, Taline V, Toll, Lawrence, Husbands, Stephen M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188691/
https://ncbi.nlm.nih.gov/pubmed/21866885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm2003238
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