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Individualizing anti-metabolic treatment strategies for head and neck squamous cell carcinoma based on TP53 mutational status
BACKGROUND: Mutations in the TP53 tumor suppressor gene are common in HNSCC and correlate with radioresistance. Currently, there are no clinically available therapeutic approaches targeting p53 in HNSCC. Here we propose a strategy which uses TP53 mutational status to individualize anti-metabolic str...
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| Main Authors: | , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3188683/ https://ncbi.nlm.nih.gov/pubmed/21720999 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.26321 |
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