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The Energy Landscape Analysis of Cancer Mutations in Protein Kinases

The growing interest in quantifying the molecular basis of protein kinase activation and allosteric regulation by cancer mutations has fueled computational studies of allosteric signaling in protein kinases. In the present study, we combined computer simulations and the energy landscape analysis of...

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Detalhes bibliográficos
Main Authors: Dixit, Anshuman, Verkhivker, Gennady M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3188581/
https://ncbi.nlm.nih.gov/pubmed/21998754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0026071
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