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An important function of Nrf2 in combating oxidative stress: Detoxification of acetaminophen
Nrf2, a member of the “cap ‘n collar” group of transcription factors, is important for protecting cells against oxidative damage. We investigated its role in the detoxification of acetaminophen [N-acetyl-p-aminophenol (APAP)]-induced hepatotoxicity. When Nrf2 knockout (Nrf2(−/−)) and wild-type mice...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC31882/ https://ncbi.nlm.nih.gov/pubmed/11287661 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.081082098 |
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