Direct Translocation as Major Cellular Uptake for CADY Self-Assembling Peptide-Based Nanoparticles

Cell penetrating peptides constitute a potent approach to overcome the limitations of in vivo siRNA delivery. We recently proposed a peptide-based nanoparticle system, CADY, for efficient delivery of siRNA into numerous cell lines. CADY is a secondary amphipathic peptide that forms stable complexes...

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Detalles Bibliográficos
Autores principales: Rydström, Anna, Deshayes, Sébastien, Konate, Karidia, Crombez, Laurence, Padari, Kärt, Boukhaddaoui, Hassan, Aldrian, Gudrun, Pooga, Margus, Divita, Gilles
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2011
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187819/
https://ncbi.nlm.nih.gov/pubmed/21998722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025924
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