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Targeting cyclin B1 through peptide-based delivery of siRNA prevents tumour growth

The development of short interfering RNA (siRNA), has provided great hope for therapeutic targeting of specific genes responsible for patholological disorders. However, the poor cellular uptake and bioavailability of siRNA remain a major obstacle to their clinical development and most strategies tha...

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Detalhes bibliográficos
Main Authors: Crombez, Laurence, Morris, May Catherine, Dufort, Sandrine, Aldrian-Herrada, Gudrun, Nguyen, Quan, Mc Master, Gary, Coll, Jean-Luc, Heitz, Frederic, Divita, Gilles
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2724276/
https://ncbi.nlm.nih.gov/pubmed/19483097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp451
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