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3′UTR-Mediated Gene Silencing of the Mixed Lineage Leukemia (MLL) Gene
Translocations involving the Mixed Lineage Leukemia (MLL) gene generate in-frame fusions of MLL with more than 50 different partner genes (PGs). Common to all MLL translocations is the exchange not only of coding regions, but also of MLL and PG 3′-untranslated regions (3′UTRs). As a result, the MLL-...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Public Library of Science
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3187771/ https://ncbi.nlm.nih.gov/pubmed/21998658 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025449 |
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