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Methylphosphonates as probes of protein-nucleic acid interactions.

Deoxydinucleoside methylphosphonates were prepared by chemical synthesis and were introduced stereospecifically into the lac operator at two sites. These sites within d(ApApTpTpGpTpGpApGpCpGpGpApTpApApCpApApTpT), segment I, and d(ApApTpTpGpTpTpApTpCpCpGpCpTpCpApCpApApTpT), segment II, are indicated...

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Autors principals: Noble, S A, Fisher, E F, Caruthers, M H
Format: Artigo
Idioma:Inglês
Publicat: 1984
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC318753/
https://ncbi.nlm.nih.gov/pubmed/6718253
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