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Norovirus RNA-Dependent RNA Polymerase Is Phosphorylated by an Important Survival Kinase, Akt

Viruses commonly use host cell survival mechanisms to their own advantage. We show that Akt, an important signaling kinase involved in cell survival, phosphorylates the RNA-dependent RNA polymerase (RdRp) from norovirus, the major cause of gastroenteritis outbreaks worldwide. The Akt phosphorylation...

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書誌詳細
主要な著者: Eden, John-Sebastian, Sharpe, Laura J., White, Peter A., Brown, Andrew J.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2011
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187498/
https://ncbi.nlm.nih.gov/pubmed/21849454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.05562-11
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