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Norovirus RNA Synthesis Is Modulated by an Interaction between the Viral RNA-Dependent RNA Polymerase and the Major Capsid Protein, VP1

Using a cell-based assay for RNA synthesis by the RNA-dependent RNA polymerase (RdRp) of noroviruses, we previously observed that VP1, the major structural protein of the human GII.4 norovirus, enhanced the GII.4 RdRp activity but not that of the related murine norovirus (MNV) or other unrelated RNA...

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Bibliografische gegevens
Hoofdauteurs: Subba-Reddy, Chennareddy V., Yunus, Muhammad Amir, Goodfellow, Ian G., Kao, C. Cheng
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446604/
https://ncbi.nlm.nih.gov/pubmed/22787222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01208-12
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