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Norovirus RNA Synthesis Is Modulated by an Interaction between the Viral RNA-Dependent RNA Polymerase and the Major Capsid Protein, VP1

Using a cell-based assay for RNA synthesis by the RNA-dependent RNA polymerase (RdRp) of noroviruses, we previously observed that VP1, the major structural protein of the human GII.4 norovirus, enhanced the GII.4 RdRp activity but not that of the related murine norovirus (MNV) or other unrelated RNA...

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Bibliografiske detaljer
Main Authors: Subba-Reddy, Chennareddy V., Yunus, Muhammad Amir, Goodfellow, Ian G., Kao, C. Cheng
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446604/
https://ncbi.nlm.nih.gov/pubmed/22787222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01208-12
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