Norovirus RNA Synthesis Is Modulated by an Interaction between the Viral RNA-Dependent RNA Polymerase and the Major Capsid Protein, VP1

Using a cell-based assay for RNA synthesis by the RNA-dependent RNA polymerase (RdRp) of noroviruses, we previously observed that VP1, the major structural protein of the human GII.4 norovirus, enhanced the GII.4 RdRp activity but not that of the related murine norovirus (MNV) or other unrelated RNA...

Full description

Saved in:
Bibliographic Details
Main Authors: Subba-Reddy, Chennareddy V., Yunus, Muhammad Amir, Goodfellow, Ian G., Kao, C. Cheng
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3446604/
https://ncbi.nlm.nih.gov/pubmed/22787222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01208-12
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items