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Phosphotyrosine-Dependent Coupling of Tim-3 to T-Cell Receptor Signaling Pathways
The transmembrane protein Tim-3 has been shown to negatively regulate T-cell-dependent immune responses and was recently demonstrated to be associated with the phenomenon of immune exhaustion, which can occur as a consequence of chronic viral infection. Unlike other negative regulators of T-cell fun...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3187355/ https://ncbi.nlm.nih.gov/pubmed/21807895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05297-11 |
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