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QKI-Mediated Alternative Splicing of the Histone Variant MacroH2A1 Regulates Cancer Cell Proliferation

The histone variant macroH2A1 contains a carboxyl-terminal ∼30-kDa domain called a macro domain. MacroH2A1 is produced as one of two alternatively spliced forms, macroH2A1.1 and macroH2A1.2. While the macro domain of macroH2A1.1 can interact with NAD(+)-derived small molecules, such as poly(ADP-ribo...

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Detalhes bibliográficos
Main Authors: Novikov, Leonid, Park, Jong Woo, Chen, Hongshan, Klerman, Hadassa, Jalloh, Abubakar S., Gamble, Matthew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187283/
https://ncbi.nlm.nih.gov/pubmed/21844227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.05244-11
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