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Specificity and Role of the Borrelia burgdorferi CtpA Protease in Outer Membrane Protein Processing

To further characterize the function of the Borrelia burgdorferi C-terminal protease CtpA, we used site-directed mutagenesis to alter the putative CtpA cleavage site of one of its known substrates, the outer membrane (OM) porin P13. These mutations resulted in only partial blockage of P13 processing...

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Bibliografiske detaljer
Main Authors: Kumru, Ozan S., Bunikis, Ignas, Sorokina, Irina, Bergström, Sven, Zückert, Wolfram R.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187231/
https://ncbi.nlm.nih.gov/pubmed/21856844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.05622-11
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