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Translocation of Borrelia burgdorferi Surface Lipoprotein OspA Through the Outer Membrane Requires an Unfolded Conformation and Can Initiate at the C-terminus

Borrelia burgdorferi surface lipoproteins are essential to the pathogenesis of Lyme borreliosis, but the mechanisms responsible for their localization are only beginning to emerge. We have previously demonstrated the critical nature of the amino-terminal ‘tether’ domain of the mature lipoprotein for...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schulze, Ryan J., Chen, Shiyong, Kumru, Ozan S., Zückert, Wolfram R.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999405/
https://ncbi.nlm.nih.gov/pubmed/20398211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2958.2010.07172.x
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