A Conformational Change of C Fragment of Tetanus Neurotoxin Reduces Its Ganglioside-Binding Activity but Does Not Destroy Its Immunogenicity

The C fragment of tetanus neurotoxin (TeNT-Hc) with different conformations was observed due to the four cysteine residues within it which could form different intramolecular disulfide bonds. In this study, we prepared and compared three types of monomeric TeNT-Hc with different conformational compo...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Yu, Rui, Yi, Shaoqiong, Yu, Changming, Fang, Ting, Liu, Shuling, Yu, Ting, Song, Xiaohong, Fu, Ling, Hou, Lihua, Chen, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Vaccine Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3187031/
https://ncbi.nlm.nih.gov/pubmed/21813664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/CVI.05244-11
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados