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In Vitro Selection of Variants Resistant to β-Lactams plus β-Lactamase Inhibitors in CTX-M β-Lactamases: Predicting the In Vivo Scenario?

CTX-M β-lactamases are the most prevalent group of enzymes within the extended-spectrum β-lactamases (ESBL). The therapeutic options for CTX-M-carrying isolates are scarce, forcing the reexamination of the therapeutic possibilities of β-lactams plus β-lactamase inhibitors (BBLIs). Inhibitor-resistan...

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Autores principales: Ripoll, Aida, Baquero, Fernando, Novais, Ângela, Rodríguez-Domínguez, Mario J., Turrientes, Maria-Carmen, Cantón, Rafael, Galán, Juan-Carlos
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186957/
https://ncbi.nlm.nih.gov/pubmed/21788458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00178-11
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