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Mutational Events in Cefotaximase Extended-Spectrum β-Lactamases of the CTX-M-1 Cluster Involved in Ceftazidime Resistance

CTX-M β-lactamases, which show a high cefotaxime hydrolytic activity, constitute the most prevalent extended-spectrum β-lactamase (ESBL) type found among clinical isolates. The recent explosive diversification of CTX-M enzymes seems to have taken place due to the appearance of more efficient enzymes...

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Detalhes bibliográficos
Main Authors: Novais, Ângela, Cantón, Rafael, Coque, Teresa M., Moya, Andrés, Baquero, Fernando, Galán, Juan Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2443914/
https://ncbi.nlm.nih.gov/pubmed/18443114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01658-07
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