Evolutionary Trajectories of Beta-Lactamase CTX-M-1 Cluster Enzymes: Predicting Antibiotic Resistance

Extended-spectrum beta-lactamases (ESBL) constitute a key antibiotic-resistance mechanism affecting Gram-negative bacteria, and also an excellent model for studying evolution in real time. A shift in the epidemiology of ESBLs is being observed, which is characterized by the explosive diversification...

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Detalhes bibliográficos
Main Authors: Novais, Ângela, Comas, Iñaki, Baquero, Fernando, Cantón, Rafael, Coque, Teresa M., Moya, Andrés, González-Candelas, Fernando, Galán, Juan-Carlos
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809773/
https://ncbi.nlm.nih.gov/pubmed/20107608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000735
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