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MD-2 interacts with Lyn kinase and is tyrosine phosphorylated following LPS-induced activation of the Toll-like receptor 4 signaling pathway

Stimulation with LPS induces tyrosine phosphorylation of numerous proteins involved in the TLR signaling pathway. In this study, we demonstrate that MD-2 is also tyrosine phosphorylated following LPS stimulation. LPS-induced tyrosine phosphorylation of MD-2 is specific, it is blocked by the tyrosine...

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書誌詳細
主要な著者: Gray, Pearl, Dagvadorj, Jargalsaikhan, Michelsen, Kathrin S., Brikos, Constantinos, Rentsendorj, Altan, Town, Terrence, Crother, Timothy R., Arditi, Moshe
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186846/
https://ncbi.nlm.nih.gov/pubmed/21918188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1100890
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