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Detection and identification of mutagens and carcinogens as their adducts with guanosine derivatives.

For use in screening for environmental mutagens and carcinogens, a highly fluorescent derivative of guanosine, 2'-deoxy-2'-(2",3"-dihydro-2",4"-diphenyl-2"-hydroxy-3"-oxo-1"-pyrrol yl) guanosine (FG), was synthesized. When incubated with FG in aqueous solution, mutagens form adducts that can be anal...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Kasai, H, Hayami, H, Yamaizumi, Z, SaitôH, Nishimura, S
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 1984
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC318645/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6701096/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/12.4.2127
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