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Detection and identification of mutagens and carcinogens as their adducts with guanosine derivatives.

For use in screening for environmental mutagens and carcinogens, a highly fluorescent derivative of guanosine, 2'-deoxy-2'-(2",3"-dihydro-2",4"-diphenyl-2"-hydroxy-3"-oxo-1"-pyrrol yl) guanosine (FG), was synthesized. When incubated with FG in aqueous sol...

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Autors principals: Kasai, H, Hayami, H, Yamaizumi, Z, SaitôH, Nishimura, S
Format: Artigo
Idioma:Inglês
Publicat: 1984
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC318645/
https://ncbi.nlm.nih.gov/pubmed/6701096
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