Detection and identification of mutagens and carcinogens as their adducts with guanosine derivatives.
For use in screening for environmental mutagens and carcinogens, a highly fluorescent derivative of guanosine, 2'-deoxy-2'-(2",3"-dihydro-2",4"-diphenyl-2"-hydroxy-3"-oxo-1"-pyrrol yl) guanosine (FG), was synthesized. When incubated with FG in aqueous solution, mutagens form adducts that can be anal...
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| Udgivet i: | Nucleic Acids Res |
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| Principais autores: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
1984
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| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC318645/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6701096/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/12.4.2127 |
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