Muscle Creatine Kinase Deficiency Triggers Both Actin Depolymerization and Desmin Disorganization by Advanced Glycation End Products in Dilated Cardiomyopathy

Alterations in the balance of cytoskeleton as well as energetic proteins are involved in the cardiac remodeling occurring in dilated cardiomyopathy (DCM). We used two-dimensional DIGE proteomics as a discovery approach to identify key molecular changes taking place in a temporally controlled model o...

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Bibliographische Detailangaben
Hauptverfasser: Diguet, Nicolas, Mallat, Youssef, Ladouce, Romain, Clodic, Gilles, Prola, Alexandre, Tritsch, Eva, Blanc, Jocelyne, Larcher, Jean-Christophe, Delcayre, Claude, Samuel, Jane-Lise, Friguet, Bertrand, Bolbach, Gérard, Li, Zhenlin, Mericskay, Mathias
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Molecular Bases of Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186397/
https://ncbi.nlm.nih.gov/pubmed/21768101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.252395
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