Muscle Creatine Kinase Deficiency Triggers Both Actin Depolymerization and Desmin Disorganization by Advanced Glycation End Products in Dilated Cardiomyopathy

Alterations in the balance of cytoskeleton as well as energetic proteins are involved in the cardiac remodeling occurring in dilated cardiomyopathy (DCM). We used two-dimensional DIGE proteomics as a discovery approach to identify key molecular changes taking place in a temporally controlled model o...

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Main Authors: Diguet, Nicolas, Mallat, Youssef, Ladouce, Romain, Clodic, Gilles, Prola, Alexandre, Tritsch, Eva, Blanc, Jocelyne, Larcher, Jean-Christophe, Delcayre, Claude, Samuel, Jane-Lise, Friguet, Bertrand, Bolbach, Gérard, Li, Zhenlin, Mericskay, Mathias
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2011
Teme:
Molecular Bases of Disease
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186397/
https://ncbi.nlm.nih.gov/pubmed/21768101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.252395
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