Muscle Creatine Kinase Deficiency Triggers Both Actin Depolymerization and Desmin Disorganization by Advanced Glycation End Products in Dilated Cardiomyopathy

Alterations in the balance of cytoskeleton as well as energetic proteins are involved in the cardiac remodeling occurring in dilated cardiomyopathy (DCM). We used two-dimensional DIGE proteomics as a discovery approach to identify key molecular changes taking place in a temporally controlled model o...

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Detalhes bibliográficos
Main Authors: Diguet, Nicolas, Mallat, Youssef, Ladouce, Romain, Clodic, Gilles, Prola, Alexandre, Tritsch, Eva, Blanc, Jocelyne, Larcher, Jean-Christophe, Delcayre, Claude, Samuel, Jane-Lise, Friguet, Bertrand, Bolbach, Gérard, Li, Zhenlin, Mericskay, Mathias
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Molecular Bases of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186397/
https://ncbi.nlm.nih.gov/pubmed/21768101
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.252395
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