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Contributions of Conserved Residues at the Gating Interface of Glycine Receptors

Glycine receptors (GlyRs) are chloride channels that mediate fast inhibitory neurotransmission and are members of the pentameric ligand-gated ion channel (pLGIC) family. The interface between the ligand binding domain and the transmembrane domain of pLGICs has been proposed to be crucial for channel...

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Main Authors: Pless, Stephan A., Leung, Ada W. Y., Galpin, Jason D., Ahern, Christopher A.
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186368/
https://ncbi.nlm.nih.gov/pubmed/21835920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.269027
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