Glycosaminoglycans and Glucose Prevent Apoptosis in 4-Methylumbelliferone-treated Human Aortic Smooth Muscle Cells

Smooth muscle cells (SMCs) have a pivotal role in cardiovascular diseases and are responsible for hyaluronan (HA) deposition in thickening vessel walls. HA regulates SMC proliferation, migration, and inflammation, which accelerates neointima formation. We used the HA synthesis inhibitor 4-methylumbe...

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Detalhes bibliográficos
Main Authors: Vigetti, Davide, Rizzi, Manuela, Moretto, Paola, Deleonibus, Sara, Dreyfuss, Jonathan M., Karousou, Evgenia, Viola, Manuela, Clerici, Moira, Hascall, Vincent C., Ramoni, Marco F., De Luca, Giancarlo, Passi, Alberto
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Glycobiology and Extracellular Matrices
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3186361/
https://ncbi.nlm.nih.gov/pubmed/21768115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.266312
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