Hyaluronan Synthesis Is Inhibited by Adenosine Monophosphate-activated Protein Kinase through the Regulation of HAS2 Activity in Human Aortic Smooth Muscle Cells

Hyaluronan (HA) is an extracellular matrix glycosaminoglycan (GAG) involved in cell motility, proliferation, tissue remodeling, development, differentiation, inflammation, tumor progression, and invasion and controls vessel thickening in cardiovascular diseases. Therefore, the control of HA synthesi...

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Autors principals: Vigetti, Davide, Clerici, Moira, Deleonibus, Sara, Karousou, Evgenia, Viola, Manuela, Moretto, Paola, Heldin, Paraskevi, Hascall, Vincent C., De Luca, Giancarlo, Passi, Alberto
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Glycobiology and Extracellular Matrices
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3048678/
https://ncbi.nlm.nih.gov/pubmed/21228273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.193656
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