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Reduced ribosomal protein gene dosage and p53 activation in low-risk myelodysplastic syndrome
Reduced gene dosage of ribosomal protein subunits has been implicated in 5q− myelodysplastic syndrome and Diamond Blackfan anemia, but the cellular and pathophysiologic defects associated with these conditions are enigmatic. Using conditional inactivation of the ribosomal protein S6 gene in laborato...
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| 主要な著者: | , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society of Hematology
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3186336/ https://ncbi.nlm.nih.gov/pubmed/21788341 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-11-318584 |
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