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Reduced NR4A gene dosage leads to mixed myelodysplastic/myeloproliferative neoplasms in mice

The NR4A subfamily of nuclear receptors (NR4A1, NR4A2, and NR4A3) function as transcription factors that transduce diverse extracellular signals into altered gene transcription to coordinate apoptosis, proliferation, cell cycle arrest, and DNA repair. We previously discovered that 2 of these recepto...

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Detalhes bibliográficos
Main Authors: Ramirez-Herrick, Ashley M., Mullican, Shannon E., Sheehan, Andrea M., Conneely, Orla M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3062356/
https://ncbi.nlm.nih.gov/pubmed/21205929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-02-267906
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