Astrocytic P2Y(1) receptor is involved in the regulation of cytokine/chemokine transcription and cerebral damage in a rat model of cerebral ischemia

After brain ischemia, significant amounts of adenosine 5′-triphosphate are released or leaked from damaged cells, thus activating purinergic receptors in the central nervous system. A number of P2X/P2Y receptors have been implicated in ischemic conditions, but to date the P2Y(1) receptor (P2Y(1)R) h...

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Main Authors: Kuboyama, Kazuya, Harada, Hideki, Tozaki-Saitoh, Hidetoshi, Tsuda, Makoto, Ushijima, Kazuo, Inoue, Kazuhide
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2011
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Original Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185880/
https://ncbi.nlm.nih.gov/pubmed/21487414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2011.49
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