Reduced spinal microglial activation and neuropathic pain after nerve injury in mice lacking all three nitric oxide synthases

BACKGROUND: Several studies have investigated the involvement of nitric oxide (NO) in acute and chronic pain using mice lacking a single NO synthase (NOS) gene among the three isoforms: neuronal (nNOS), inducible (iNOS) and endothelial (eNOS). However, the precise role of NOS/NO in pain states remai...

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Autors principals: Kuboyama, Kazuya, Tsuda, Makoto, Tsutsui, Masato, Toyohara, Yumiko, Tozaki-Saitoh, Hidetoshi, Shimokawa, Hiroaki, Yanagihara, Nobuyuki, Inoue, Kazuhide
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3152900/
https://ncbi.nlm.nih.gov/pubmed/21756313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-7-50
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