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Assaying β-amyloid Toxicity using a Transgenic C. elegans Model

Accumulation of the β-amyloid peptide (Aβ) is generally believed to be central to the induction of Alzheimer's disease, but the relevant mechanism(s) of toxicity are still unclear. Aβ is also deposited intramuscularly in Inclusion Body Myositis, a severe human myopathy. The intensely studied ne...

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Bibliografische gegevens
Hoofdauteurs: Dostal, Vishantie, Link, Christopher D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MyJove Corporation 2010
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185644/
https://ncbi.nlm.nih.gov/pubmed/20972410
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2252
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