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Assaying β-amyloid Toxicity using a Transgenic C. elegans Model
Accumulation of the β-amyloid peptide (Aβ) is generally believed to be central to the induction of Alzheimer's disease, but the relevant mechanism(s) of toxicity are still unclear. Aβ is also deposited intramuscularly in Inclusion Body Myositis, a severe human myopathy. The intensely studied ne...
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Format: | Artigo |
Sprache: | Inglês |
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MyJove Corporation
2010
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Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3185644/ https://ncbi.nlm.nih.gov/pubmed/20972410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/2252 |
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