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Broad-spectrum aptamer inhibitors of HIV reverse transcriptase closely mimic natural substrates
A detailed understanding of how aptamers recognize biological binding partners is of considerable importance in the development of oligonucleotide therapeutics. For antiviral nucleic acid aptamers, current models predict a correlation between broad-spectrum inhibition of viral proteins and suppressi...
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| Auteurs principaux: | , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Oxford University Press
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3185408/ https://ncbi.nlm.nih.gov/pubmed/21727088 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkr381 |
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