Long-Range Massively Parallel Mate Pair Sequencing Detects Distinct Mutations and Similar Patterns of Structural Mutability in Two Breast Cancer Cell Lines

Cancer genomes frequently undergo genomic instability resulting in accumulation of chromosomal rearrangement. To date, one of the main challenges has been to confidently and accurately identify these rearrangements using short-read massively parallel sequencing. We were able to improve cancer rearra...

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Main Authors: Hampton, Oliver A., Miller, Christopher A., Koriabine, Maxim, Li, Jian, Hollander, Petra Den, Carbone, Lucia, Nefedov, Mikhail, Ten Hallers, Boudewijn F.H., Lee, Adrian V., De Jong, Pieter J., Milosavljevic, Aleksandar
格式: Artigo
語言:Inglês
出版: 2011
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185296/
https://ncbi.nlm.nih.gov/pubmed/21962895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cancergen.2011.07.009
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