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Prion protein: Evolution caught en route
The prion protein displays a unique structural ambiguity in that it can adopt multiple stable conformations under physiological conditions. In our view, this puzzling feature resulted from a sudden environmental change in evolution when the prion, previously an integral membrane protein, got expelle...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2001
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC31852/ https://ncbi.nlm.nih.gov/pubmed/11287647 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.071308398 |
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