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The role of dimerization in prion replication.

The central theme in prion diseases is the conformational transition of a cellular protein from a physiologic to a pathologic (so-called scrapie) state. Currently, two alternative models exist for the mechanism of this autocatalytic process; in the template assistance model the prion is assumed to b...

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Bibliografische gegevens
Hoofdauteurs: Tompa, Peter, Tusnády, Gábor E, Friedrich, Peter, Simon, István
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2002
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1301970/
https://ncbi.nlm.nih.gov/pubmed/11916832
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