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Processing of DNA structures via DNA unwinding and branch migration by the S. cerevisiae Mph1 protein

The budding yeast Mph1 protein, the putative ortholog of human FANCM, possesses a 3′ to 5′ DNA helicase activity and is capable of disrupting the D-loop structure to suppress chromosome arm crossovers in mitotic homologous recombination. Similar to FANCM, genetic studies have implicated Mph1 in DNA...

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Hlavní autoři: Zheng, Xiao-Feng, Prakash, Rohit, Saro, Dorina, Longerich, Simonne, Niu, Hengyao, Sung, Patrick
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185188/
https://ncbi.nlm.nih.gov/pubmed/21880555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2011.08.002
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