TMPRSS2-ERG Status in Circulating Tumor Cells as a Predictive Biomarker of Sensitivity in Castration-Resistant Prostate Cancer Patients Treated With Abiraterone Acetate

BACKGROUND: Abiraterone acetate (AA) is an androgen biosynthesis inhibitor shown to prolong life in patients with castration-resistant prostate cancer (CRPC) already treated with chemotherapy. AA treatment results in dramatic declines in prostate-specific antigen (PSA) in some patients and no declin...

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Hauptverfasser: Danila, Daniel C., Anand, Aseem, Sung, Clifford C., Heller, Glenn, Leversha, Margaret A., Cao, Long, Lilja, Hans, Molina, Arturo, Sawyers, Charles L., Fleisher, Martin, Scher, Howard I.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3185163/
https://ncbi.nlm.nih.gov/pubmed/21802835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.eururo.2011.07.011
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