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Extracellular ATP stimulates epithelial cell motility through Pyk2-mediated activation of the EGF receptor

Wounding usually causes considerable cell damage, and released ATP promotes migration of nearby epithelium. ATP binds to purinergic receptors on the cell surface and induces transactivation of the EGF receptor through signaling by the Src family kinases (SFKs). Here we tested whether ATP activates t...

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Détails bibliographiques
Auteurs principaux: Block, Ethan R., Tolino, Michael A., Klarlund, Jes K.
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3184351/
https://ncbi.nlm.nih.gov/pubmed/21840393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2011.07.021
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