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Pyk2 Activation Triggers Epidermal Growth Factor Receptor Signaling and Cell Motility after Wounding Sheets of Epithelial Cells

Activation of the epidermal growth factor receptor (EGFR) is a key signaling event that promotes cells to move and cover wounds in many epithelia. We have previously shown that wounding activates the EGFR through activation of the Src family kinases (SFKs), which induce proteolytic shedding of epide...

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Hlavní autoři: Block, Ethan R., Tolino, Michael A., Klarlund, Jes K.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2859496/
https://ncbi.nlm.nih.gov/pubmed/20215112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.083089
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